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Gum disease and kidney health: could your diet be making it worse?

NCT ID NCT07427069

Knowledge-focused Sponsor: Recep Tayyip Erdogan University Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study looks at whether a diet that promotes inflammation can make gum disease worse in people with chronic kidney disease. Researchers will assess the diets and gum health of 100 adults with kidney disease. The goal is to understand if eating more inflammatory foods is linked to more severe gum problems, which could lead to better dietary advice for patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it succeeds, this could point toward dietary changes as a way to help manage gum disease in people with chronic kidney disease.
What could go wrong
This is an observational study, not a treatment trial. It can show links but cannot prove cause and effect. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with chronic kidney disease who come to the Periodontology Clinic of Recep Tayyip Erdoğan University Faculty of Dentistry for routine periodontal treatment

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being between 18 and 65 years of age * Being diagnosed with Chronic Kidney Disease (having an eGFR below 60 ml/min/1.73 m² for at least 3 months or a urine albumin-to-creatinine ratio above 30 mg/g (proteinuria)) * Having at least 20 teeth * Not having received periodontal therapy in the last 6 months * Not having taken antibiotics, steroids, and/or nonsteroidal anti-inflammatory drugs in the last 3 weeks * Not having any autoimmune disease, osteoporosis, or cancer * Not taking immunosuppressive medications, oral contraceptives, Not taking bisphosphonates * Not being pregnant * Not having an active infectious disease (acute hepatitis, tuberculosis, AIDS) * Not taking chronic medications that affect periodontal tissues (cyclosporine A, phenytoin) * Not taking antioxidant supplements in the last 6 months Exclusion Criteria: * Patients with an active infectious disease, * Those taking medications that could affect periodontal tissues, * History of endocarditis, * Recent antibiotic use (within 4 months), * Alcohol/drug use, * Psychological disorders, * Eating disorders, * Dementia, * Pregnancy and breastfeeding, * Patients who did not sign the informed consent form

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome Inflammation periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney disease Diet, food and nutrition Periodontitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Periodontology of the Faculty of Dentistry of Recep Tayyip Erdogan University

    Rize, Rize Province, 53200, Turkey (Türkiye)

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