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Can a Two-Day diet change help fight brain cancer?

NCT ID NCT07553520

First seen Apr 29, 2026 · Last updated Jun 23, 2026 · Updated 12 times

Summary

This pilot study aimed to see if a diet low in two specific nutrients (cysteine and methionine) could affect metabolism in patients with recurrent gliomas. Up to 30 participants were to be randomly assigned to either a normal diet or the special diet for 2, 4, or 7 days before standard treatment. Researchers planned to measure changes in blood, urine, and tumor samples to understand how the diet impacts cancer cells. However, the study was withdrawn before enrolling any participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of North Carolina at Chapel Hill, Department of Radiation Oncology

    Chapel Hill, North Carolina, 27514, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cysteine/methionine deprivation (CMD) diet

What this could lead to

If successful, this could point toward a dietary approach to help manage brain tumors by altering cancer cell metabolism.

What could go wrong

This is a very early pilot study with no participants enrolled, so results are uncertain. The diet is short-term and may not affect tumor growth or survival.

Conditions

The condition(s) this trial relates to.

glioblastoma glioma glioma susceptibility 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.