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Blood clot score may predict organ damage in septic shock

NCT ID NCT06363149

Knowledge-focused Sponsor: Sanjay Gandhi Postgraduate Institute of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

Septic shock is a life-threatening condition where infection leads to dangerously low blood pressure. Many patients also develop disseminated intravascular coagulation (DIC), a disorder that causes abnormal blood clotting throughout the body. This study will follow 60 adults in the ICU to see whether changes in a standard DIC score are linked to worsening organ function over two weeks. The goal is to help doctors identify high-risk patients earlier and guide more timely interventions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a clear link is found, doctors might use DIC scores to predict organ failure earlier and start treatment sooner in septic shock patients.
What could go wrong
This is a small, observational study at a single center, so results may not apply to all patients. It looks for patterns, not a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Apr 2024

Finished

Aug 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult ICU patients having septic shock as defined by Sepsis -3 definition requiring vasopressor for at least 12 hours duration will be considered.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult ICU patients having septic shock as defined by Sepsis -3 definition requiring vasopressor for at least 12 hours duration will be considered. Exclusion Criteria: * Patient having septic shock duration either less than 12 hours or more than 24 hours at the time of the inclusion * Age less than 18 years or more than 65 years * Expected survival less than 72 hours * Caregiver refused for the consent to participate in the study

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Conditions

The condition(s) this trial relates to.

Critical Illness disseminated intravascular coagulation multiple organ dysfunction syndrome toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Disseminated intravascular coagulation Septic shock

Contacts and locations

Locations

  • Sanjay Gandhi Postgraduate Institute of Medical Sciences

    Lucknow, Uttar Pradesh, 226014, India

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