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Sugar water shot may ease stroke shoulder pain

NCT ID NCT06988228

Symptom relief Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether injecting a 15% dextrose (sugar water) solution into the shoulder could reduce pain and improve movement in stroke survivors with hemiplegic shoulder pain. Forty participants received either dextrose injections or a placebo (salt water) over three sessions, plus exercise therapy. The main goal was to measure pain changes at rest, after exercise, and during daily activities up to three months later.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
15% dextrose solution
What this could lead to
If it works, this could offer a simple, low-cost injection to ease shoulder pain and improve mobility after a stroke.
What could go wrong
This is a small, completed trial with only 40 participants, so results may not apply to everyone. The placebo group also received exercise therapy, making it hard to know how much the dextrose alone helps.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Dec 2024

Finished

Sep 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients aged between 40 and 75 years History of stroke Brunnstrom stage 2 or higher in the upper extremity Provided written informed consent and agreed to participate in the study Exclusion Criteria: History of any prior injection therapy to the shoulder region Previous radiotherapy or surgery involving the shoulder Pre-stroke shoulder pain History of shoulder surgery History of inflammatory joint disease Presence of neuromuscular disorders Full-thickness rotator cuff tear Patients with aphasia or severe cognitive impairment Presence of pectoral muscle spasticity Active malignancy with acute inflammation at the treatment site Known coagulation disorder with INR ≥ 4 Presence of vascular conditions such as deep vein thrombosis, phlebitis, varicose veins, or arterial disease in the affected limb

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemiplegic shoulder pain Stroke

Contacts and locations

Locations

  • Istanbul Physical Medicine and Rehabilitation Training and Research Hospital

    Istanbul, bahçelievler, 34186, Turkey (Türkiye)

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