Sugar water shot may ease stroke shoulder pain

NCT ID NCT06988228

Completed Symptom relief Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether injecting a 15% dextrose (sugar water) solution into the shoulder could reduce pain and improve movement in stroke survivors with hemiplegic shoulder pain. Forty participants received either dextrose injections or a placebo (salt water) over three sessions, plus exercise therapy. The main goal was to measure pain changes at rest, after exercise, and during daily activities up to three months later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 15% dextrose solution
What this could lead to: If it works, this could offer a simple, low-cost injection to ease shoulder pain and improve mobility after a stroke.
What could go wrong: This is a small, completed trial with only 40 participants, so results may not apply to everyone. The placebo group also received exercise therapy, making it hard to know how much the dextrose alone helps.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMIPLEGIC SHOULDER PAIN STROKE

Contacts and locations

Locations

Istanbul Physical Medicine and Rehabilitation Training and Research Hospital

Istanbul, bahçelievler, 34186, Turkey (Türkiye)

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