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Could an ADHD drug help curb cocaine addiction?

NCT ID NCT05529927

First seen Mar 20, 2026 · Last updated Jun 16, 2026 · Updated 14 times

Summary

This study tests whether a slow-release form of dexamphetamine, a drug used for ADHD, can help people with cocaine and opioid addiction reduce their cocaine use. About 204 adults who are already on methadone for opioid addiction will receive either dexamphetamine or a placebo for 24 weeks. The goal is to see if this approach increases days of cocaine abstinence and improves overall health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brijder Den Haag

    RECRUITING

    The Hague, 2512 HN, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

cocaine dependence opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.