Which drug works best for Post-C-Section nausea? study pits dexamethasone against ondansetron
NCT ID NCT05692245
First seen Mar 22, 2026 · Last updated Jun 22, 2026 · Updated 16 times
Summary
This study looked at 100 healthy women having a planned or non-labor cesarean delivery to see which drug works better as a first-line treatment to prevent nausea and vomiting after surgery. Participants received either dexamethasone or ondansetron, and researchers tracked how many extra medications they needed for nausea, vomiting, itching, or pain in the first 24 hours. The goal is to find the most effective option to improve comfort after C-section.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexamethasone and ondansetron
What this could lead to
If successful, this could help doctors choose the best first-line antiemetic for women after cesarean delivery, improving recovery comfort.
What could go wrong
This is a small, completed Phase 4 trial with only 100 participants, so results may not apply to all patients. Both drugs are well-known, so no major surprises are expected.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.