Spine surgery pain relief: which additive works best?
NCT ID NCT06233617
First seen May 16, 2026 · Last updated Jun 23, 2026 · Updated 3 times
Summary
This study tested whether adding dexamethasone or dexmedetomidine to a standard nerve block (erector spinae plane block) could extend pain relief after spine surgery. 90 adults undergoing lumbar spine surgery received one of the two additives or a placebo. The main goal was to see how long it took before patients needed opioid painkillers. The results could help improve pain management and reduce opioid use after surgery.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Poznan University of Medical Sciences
Poznan, Poznań, 61-701, Poland
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexamethasone and dexmedetomidine (added to a local anesthetic nerve block)
What this could lead to
If one drug works better, it could help patients stay pain-free longer after spine surgery and reduce the need for strong painkillers like opioids.
What could go wrong
This is a small, single-center study with 90 people. The results may not apply to everyone, and the drugs may not show a meaningful difference in pain relief.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.