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Could a common steroid make gallbladder surgery recovery less painful?

NCT ID NCT07182110

Symptom relief Sponsor: Makassed General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether adding dexamethasone (a steroid) to a standard numbing injection (TAP block) can improve pain control after laparoscopic gallbladder removal. About 100 adults will receive either the standard numbing medicine or the numbing medicine plus dexamethasone. The main goal is to see how long it takes before they need additional pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone added to bupivacaine (Marcaine)
What this could lead to
If it works, this could point toward a better way to manage pain after gallbladder surgery, reducing the need for strong painkillers.
What could go wrong
This is a small, early-phase trial, so results may not be conclusive. Adding dexamethasone may not provide meaningful extra pain relief and could carry rare side effects like allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult Patients * Laparoscopic Cholecystectomy Patients * Patients able to consent Exclusion Criteria: * Patients allergic to dexamethasone * Allergic to Marcaine * Hemodynamically unstable

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia Breakthrough Pain Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic cholecystectomy

Contacts and locations

Locations

  • Makassed General Hospital

    Beirut, Lebanon

More trials for these conditions

Other studies related to the condition(s) this trial covers.