Steroid trial for brain injury halted early

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * -Patients who have suffered a head injury and have one or more cerebral contusions with visible pericontusional edema in the CT scan. * Patients with brain contusions in whom non-sugical treatment has been selected initially. * Age 18 or over and under 85 * Signing of informed consent by the patient or by his legal representative. The fundamental eligibility criterion is the responsible clinician's 'uncertainty' as to whether or not to use dexamethasone in a particular patient with TBI. This pragmatic approach will allow us to see whether the intervention improves patient outcomes under real-life conditions. Exclusion Criteria: * Patients with TBI and brain contusions who have required surgery to evacuate the cerebral contusion before randomization. * Patients with TBI who have required a craniotomy before randomization for any other reason: evacuation of subdural, epidural hematoma or depressed skull fracture. * Patients with an extracranial Injury Severity Score greater than 18 points. * Patients in whom the use of corticosteroids is contraindicated. * Patients who take oral corticosteroids chronically. * Patients included in another clinical trial. * Known intolerance or hypersensitivity to dexamethasone. * Patients with allergy or intolerance to the following excipients contained in dexamethasone / placebo capsules: lactose, corn starch or microcrystalline cellulose. * Patients with a history of psychotic disorders. * Patients with inability to take medication orally due to swallowing problems in which it is not indicated to place a nasogastric tube. * Pregnant or breastfeeding patients. * Patients in a GCS 3 points situation with bilateral dilated pupils. * Patients with associated spinal cord injuries. * Patient with any systemic condition that contraindicates the use of corticosteroids.