Steroid trial for brain injury halted early
NCT ID NCT04303065
First seen Feb 06, 2026 · Last updated Jun 23, 2026 · Updated 14 times
Summary
This study aimed to see if the steroid dexamethasone could help people with traumatic brain injury who had brain contusions and swelling. It planned to enroll 600 adults, giving them a short course of dexamethasone or a placebo. The main goal was to measure recovery using the Glasgow Outcome Scale at one and six months. However, the trial was terminated early, so no conclusions could be drawn.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hospital Universitari Son Espases
Palma de Mallorca, Balearic Islands, 07120, Spain
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexamethasone (a steroid anti-inflammatory drug)
What this could lead to
If it had succeeded, this could have pointed toward a treatment to reduce brain swelling and improve recovery after head injury.
What could go wrong
The trial was terminated, so results are not available. Steroids can have side effects like infection risk, and earlier studies have shown mixed results for brain injury.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.