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Can a diabetes drug and a blood pressure pill protect hearts in vasculitis?

NCT ID NCT06887062

First seen Jan 11, 2026 · Last updated Jun 18, 2026 · Updated 26 times

Summary

This study looks at whether two medications, dapagliflozin and bosentan, can improve blood vessel function in people with large vessel vasculitis (LVV), a condition that raises the risk of heart attacks and strokes. About 60 adults with stable LVV will take both drugs for 6 weeks, then dapagliflozin alone for 4 more weeks. Researchers will measure changes in blood flow and blood pressure to see if this combination can lower cardiovascular risk.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Edinburgh

    RECRUITING

    Edinburgh, EH16 4TJ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Giant Cell Arteritis Inflammation Takayasu arteritis temporal arteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.