Talking therapy shows promise for MG patients with depression in tiny pilot study
NCT ID NCT07649187
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether having a tendency toward depression affects how well people with thymoma-associated myasthenia gravis (MG) respond to psychological counseling. Nineteen adults who had surgery for thymoma and MG received eight sessions of counseling based on Gestalt therapy and Somatic Experiencing. Researchers measured changes in daily functioning, quality of life, and well-being before and after the sessions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- psychological counseling (Gestalt therapy and Somatic Experiencing)
- What this could lead to
- If successful, this could point toward personalized counseling approaches for myasthenia gravis patients with depressive symptoms.
- What could go wrong
- This is a very small pilot study with only 19 participants and no control group, so results may not apply to everyone. The intervention is behavioral, not a drug, so effects are limited.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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19 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. A confirmed diagnosis of MG associated with thymoma and prior completion of surgical treatment 2. Age ≥ 20 years 3. Ability to communicate clearly and provide reliable responses 4. Absence of cognitive impairment or severe psychiatric illness that could interfere with participation 5. Willingness to participate in the study with provision of written informed consent Exclusion Criteria: 1. The absence of a confirmed diagnosis of myasthenia gravis 2. Failure to confirm thymoma on postoperative pathological examination 3. Inability to communicate adequately in Mandarin, Taiwanese, English, or written form 4. The presence of conditions that could compromise verbal communication or regular participation in counseling sessions, such as significant traumatic brain injury, severe psychiatric disorders, or cognitive impairment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Shin Kong Wu Ho-Su Memorial Hospital
Taipei, Taipei, 111045, Taiwan
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