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New nano varnish and laser combo could soothe sensitive teeth

NCT ID NCT07418788

Symptom relief Sponsor: Faculty of Dental Medicine for Girls Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

This study tests whether a special nano calcium fluoride varnish, a diode laser, or both together can reduce tooth sensitivity. Thirty adults with sensitive teeth will receive one of the treatments and rate their pain on a scale. The goal is to see which approach provides the best and longest-lasting relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
polymeric nano calcium fluoride varnish (OliNANO seal) and diode laser
What this could lead to
If successful, this could offer a long-lasting, non-invasive treatment option for people with sensitive teeth.
What could go wrong
This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The treatment may not provide lasting relief or could cause minor side effects like gum irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

May 2025

Finished

Jul 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Medically free * Non-smokers * Co-operative patients who will be interested in participating in the study and willing to sign the informed consent. * Availability of patients for 1 year Exclusion Criteria: * Patients currently using analgesic, anti-inflammatory medications, sedatives, tranquilizers, anticonvulsants, or any other medications that could potentially alter pain perception. * Patients undergoing orthodontic treatment. * Patients using desensitizing toothpaste * Patients receiving dentin hypersensitivity (DH) treatment * Pregnant or lactating women * Patients have high consumption of sour and acidic food * Patients who had undergone professional desensitizing therapy during the previous 3 months.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity gingival recession

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dentin hypersensitivity, non-carious cervical lesions Gingival recession localized moderate

Contacts and locations

Locations

  • Faculty of Dental medicine for Girls

    Cairo, 4470351, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.