New gel could soothe sensitive teeth without the drill
NCT ID NCT07323693
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a bioactive desensitizer gel can reduce tooth sensitivity better than a standard fluoride varnish. Thirty adults with sensitive teeth received one of the two treatments, and their pain levels were tracked over 6 months. The gel works by releasing calcium and phosphate to help seal exposed dentin.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bioactive desensitizer gel (Predicta) and sodium fluoride varnish (Proshield)
- What this could lead to
- If it works, this could offer a new, effective option for treating tooth sensitivity without drilling or injections.
- What could go wrong
- This is a small, completed trial with only 30 participants, so results may not apply to everyone. The gel may not work better than the standard varnish.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
30 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Dec 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • With ≥1 sensitive tooth and with exposed dentin in the upper or lower dental arches. * Grade IV gingival recession. * Schiff sensitivity score needed to be ≥2, indicating that application of a jet of air makes the patient respond and move or requests discontinuation of the stimuli application. Exclusion Criteria: * • Domestic or in-office fluoride application and bleaching 6 months before beginning of treatment * Long-term use of anti-inflammatory, analgesic and psychotropic drugs. * Allergies to product ingredients * Eating disorders, systemic conditions that cause or predispose patients to develop dentin hypersensitivity (for example, gastroesophageal reflux disease, GERD) * Excessive dietary or environmental exposure to acids. * Orthodontic appliance treatment within the previous three months. * Periodontal surgery within the previous three months before the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Dentistry
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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