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New toothpaste aims to soothe sensitive teeth in seconds

NCT ID NCT07057141

Symptom relief Sponsor: University of Pavia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a toothpaste and mouthwash made with biomimetic hydroxyapatite could reduce tooth sensitivity in 100 adults with receding gums. Participants had one 30-second application of either the toothpaste or mouthwash in a clinic. Sensitivity was measured before and right after using a standard air test and a pain scale.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Biomimetic hydroxyapatite toothpaste and mouthwash
What this could lead to
If effective, this could offer a simple, non-invasive way to reduce tooth sensitivity in people with receding gums.
What could go wrong
This is a small, single-application study with no long-term follow-up. Results may not apply to everyday use or to everyone with sensitivity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Jul 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female subjects aged between 18 and 70; * Subjects with gingival recession and tooth sensitivity; * Subjects who have agreed to give their free written informed consent to participate in the study. Exclusion Criteria: * Male and female subjects who are not adults; * Subjects without gingival recessions; * Subjects without dental sensitivity; * Subjects with poor participation or insufficient motivation to participate in this study.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity gingival recession

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingival recession generalized moderate Gingival recession localized moderate Tooth sensitivity

Contacts and locations

Locations

  • Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

    Pavia, Lombardy, 27100, Italy

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