Faster dental implants: is immediate loading as good as waiting?
NCT ID NCT05409287
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two ways to replace a missing lower molar with a dental implant. After the tooth is pulled and the bone heals for 12 weeks, some participants get a temporary crown right after implant surgery (immediate loading), while others wait 4 weeks before getting a temporary crown (early loading). The goal is to see if both approaches work equally well for implant survival and success after one year. About 100 adults with a lower first molar that needs extraction are taking part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2021
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 20 years * Willingness to sign informed consent and to participate in the study * Plaque index according to Silness and Loe of \< 35% \[26\] At site level: * Presence of a mandibular first molar that has to be extracted * Sufficient vertical interocclusal space for the placement of an implant crown (7 mm) * Presence of an opposing natural or artificial tooth * Ridge height sufficient for the placement of a ≥ 10 mm-long implant * Sufficient ridge width for the placement of a 4.1mm diameter implant Exclusion Criteria: At patient level: * Any physical or mental disorder that would interfere with the ability to perform adequate oral hygiene or the capability of providing written informed consent and compliance to the protocol * Any disorder that would interfere with wound healing or represent a contraindication for implant surgery such as, but not limited to, uncontrolled diabetes or conditions resulting in or requiring immunosuppression, radiation, chemotherapy, frequent use of antibiotics or antiresorptive medication such as bisphosphonates * Pregnancy or lactation * Heavy smoking habit with ≥ 10 cig/d * Severe bruxism or clenching habits, present oro-facial pain at site level * Insufficient ridge width/height for the study implant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Reconstructive Dentistry, University of Bern
Bern, 3010, Switzerland
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Other studies related to the condition(s) this trial covers.