Fat grafting before implant may improve breast reconstruction after mastectomy
NCT ID NCT04343820
First seen Feb 18, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tested a breast reconstruction method for women who had a mastectomy, with or without radiation. Surgeons first used fat grafting to prepare the chest wall, then placed a breast implant just under the skin (not under the muscle) to reduce pain and animation. The study followed 60 women for 12 months to check for complications and evaluate how the breast looked and felt.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Institut de Cancérologie de l'Ouest René Gauducheau
Saint-Herblain, 44805, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
breast reconstruction procedure (prepectoral implant with lipo-preparation)
What this could lead to
If successful, this approach could offer women a less painful breast reconstruction option with better aesthetic results and fewer complications after mastectomy.
What could go wrong
This is a small, completed feasibility study with 60 participants, so results may not apply to all patients. Complications like infection, implant removal, or poor cosmetic outcome are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.