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Can waiting a few minutes after a heart attack save more heart muscle?

NCT ID NCT01483755

Disease control Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a specific heart procedure, done a few minutes after blood flow returns naturally, can limit heart muscle damage in people having a major heart attack. 72 adults with a first heart attack and partially open arteries took part. Researchers measured heart damage using MRI scans and checked heart function after 6 months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

72 people

The number who actually took part.

Start date

Jul 2009

Finished

Jun 2012

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient \> 18 years old * Male or female * Presenting first myocardial infarction, with the beginning of pains \< 12 hours, * Requiring a revascularisation by primary angioplasty or " rescue " (after failure of thrombolysis) on LAD or RCA (not Circumflex coronary artery). * TIMI flow grade at admission of 2 or 3 * LV angiography (RAO30°) before angioplasty. Exclusion Criteria: * Cardiac arrest before the angioplasty * Cardiogenic shock * Occlusion of the artery circumflex responsible for the infarction * Visible collaterals to the area at risk * Magnetic resonance imaging: contra indication

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Conditions

The condition(s) this trial relates to.

ischemia reperfusion injury myocardial infarction Myocardial Reperfusion Injury ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myocardial reperfusion injury

Contacts and locations

Locations

  • Service d'explorations Fonctionnelles Cardiovasculaires, Hôpital Cardiologique Louis Pradel

    Bron, 69677, France

  • Service de Cardiologie, CHU d'Angers

    Angers, 49933, France

  • Service de Cardiologie, Hôpital Arnaud de Villeneuve

    Montpellier, 34295, France

  • Service de Cardiologie, Hôpital Emile Müller

    Mulhouse, 68051, France

  • Service de Cardiologie, Hôpital Rangueil

    Toulouse, 31059, France

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