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Heart surgery patients may get kidney protection from old iron drug

NCT ID NCT04633889

First seen Jan 29, 2026 · Last updated May 19, 2026 · Updated 19 times

Summary

This study tests whether a drug called deferoxamine can prevent acute kidney injury in adults undergoing heart surgery. The drug works by removing excess iron, which may damage the kidneys during surgery. About 320 participants will receive either the drug or a placebo to see if it reduces kidney problems.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.