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Could an Iron-Removing pill protect the brain after a ruptured aneurysm?

NCT ID NCT03754725

First seen Nov 06, 2025 · Last updated Jun 19, 2026 · Updated 38 times

Summary

This study tests an oral drug called deferiprone in people who have had a brain bleed from a ruptured aneurysm. The drug aims to safely remove excess iron that builds up after the bleed and may cause memory loss and brain damage. About 66 adults will receive either the drug plus standard care or standard care alone, and researchers will measure iron levels in spinal fluid, brain scans, and thinking skills over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Health System

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Univesity of Iowa Hospital and Clinics

    ACTIVE_NOT_RECRUITING

    Iowa City, Iowa, 52242, United States

Conditions

The condition(s) this trial relates to.

acquired aneurysmal subarachnoid hemorrhage dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.