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Brain pacemaker trial offers hope for Hard-to-Treat bipolar depression

NCT ID NCT06599099

First seen Feb 01, 2026 · Last updated May 21, 2026 · Updated 11 times

Summary

This study tests if deep brain stimulation (DBS) can help people with severe bipolar depression that hasn't improved with other treatments. DBS uses surgically implanted electrodes to send electrical pulses to specific brain areas. The goal is to improve mood and daily function, but this is not a cure—participants will still need ongoing care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact

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    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

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    Contact

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    Contact

  • Massachusetts General Hospital

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02114, United States

  • Rice University

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • University of Washington

    ACTIVE_NOT_RECRUITING

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.