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Extra radiation may keep breast cancer away

NCT ID NCT00907868

First seen Jan 04, 2026 · Last updated Jun 19, 2026 · Updated 35 times

Summary

This study looks at whether adding a stronger dose of radiation to the tumor site after whole-breast radiation helps prevent breast cancer from returning. About 2004 women with a very early form of breast cancer called DCIS took part. All had breast-conserving surgery and whole-breast radiation; half also got a radiation boost to the area where the tumor was removed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle

    Montpellier, 34298, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy

What this could lead to

If successful, this could show that a radiation boost lowers the chance of breast cancer coming back in women with DCIS after surgery.

What could go wrong

This is a large, late-stage trial, but the benefit of the boost may be small or come with extra side effects. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm ductal breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.