Extra radiation boost may cut recurrence risk in early breast cancer

NCT ID NCT00907868

Ongoing Disease control Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at women with a very early form of breast cancer called ductal carcinoma in situ (DCIS). After surgery to remove the cancer, all women get radiation to the whole breast. Half also get an extra, stronger dose of radiation right where the cancer was. The goal is to see if the extra dose lowers the chance of the cancer coming back. Over 2,000 women took part in this phase III trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation therapy
What this could lead to: If successful, this could show that a radiation boost lowers the chance of breast cancer coming back after surgery for early-stage DCIS.
What could go wrong: This is a large, late-stage trial, but the benefit of a boost may be small and could increase side effects. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm ductal breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle

Montpellier, 34298, France

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