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New hope for hard-to-treat breast cancer: Dato-DXd trial targets tumor growth

NCT ID NCT07205822

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This study tests a drug called Dato-DXd in people with a common type of advanced breast cancer (HR-positive, HER2-negative) that has stopped responding to hormone therapy. The goal is to see if Dato-DXd can slow or stop the cancer from growing. About 100 participants will receive the drug, and researchers will track how long the cancer stays under control and monitor side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    WITHDRAWN

    Largo, Florida, 33770, United States

  • Research Site

    RECRUITING

    Fort Wayne, Indiana, 46825, United States

  • Research Site

    RECRUITING

    Omaha, Nebraska, 68130, United States

  • Research Site

    NOT_YET_RECRUITING

    New York, New York, 10021, United States

  • Research Site

    RECRUITING

    Houston, Texas, 77024, United States

  • Research Site

    RECRUITING

    Puyallup, Washington, 98373, United States

  • Research Site

    RECRUITING

    Beijing, 100021, China

  • Research Site

    NOT_YET_RECRUITING

    Changsha, 410013, China

  • Research Site

    RECRUITING

    Guangzhou, 510060, China

  • Research Site

    RECRUITING

    Linyi, 276001, China

  • Research Site

    NOT_YET_RECRUITING

    Shandong, 250117, China

  • Research Site

    NOT_YET_RECRUITING

    Wuhan, 430071, China

  • Research Site

    NOT_YET_RECRUITING

    Zhengzhou, 450008, China

  • Research Site

    RECRUITING

    Clermont-Ferrand, 63050, France

  • Research Site

    RECRUITING

    La Roche-sur-Yon, 85925, France

  • Research Site

    RECRUITING

    Montpellier, 34070, France

  • Research Site

    RECRUITING

    Paris, 75005, France

  • Research Site

    RECRUITING

    Pierre-Bénite, 69310, France

  • Research Site

    RECRUITING

    Aviano, 33081, Italy

  • Research Site

    RECRUITING

    Florence, 50134, Italy

  • Research Site

    RECRUITING

    Meldola, 47014, Italy

  • Research Site

    RECRUITING

    Milan, 20141, Italy

  • Research Site

    RECRUITING

    Naples, 80131, Italy

  • Research Site

    RECRUITING

    Roma, 00168, Italy

  • Research Site

    RECRUITING

    Bukgu, 41404, South Korea

  • Research Site

    RECRUITING

    Goyang-si, 410-769, South Korea

  • Research Site

    RECRUITING

    Seoul, 03080, South Korea

  • Research Site

    RECRUITING

    Seoul, 06273, South Korea

  • Research Site

    RECRUITING

    Seoul, 06351, South Korea

  • Research Site

    RECRUITING

    Seoul, 06591, South Korea

  • Research Site

    RECRUITING

    Seoul, 136705, South Korea

  • Research Site

    RECRUITING

    Seoul, 3722, South Korea

  • Research Site

    RECRUITING

    Seoul, 5505, South Korea

  • Research Site

    RECRUITING

    A Coruña, 15006, Spain

  • Research Site

    RECRUITING

    Barcelona, 08035, Spain

  • Research Site

    NOT_YET_RECRUITING

    Granada, 18007, Spain

  • Research Site

    NOT_YET_RECRUITING

    Madrid, 28033, Spain

  • Research Site

    RECRUITING

    Madrid, 28040, Spain

  • Research Site

    RECRUITING

    Seville, 41009, Spain

  • Research Site

    NOT_YET_RECRUITING

    Valencia, 46009, Spain

Conditions

Explore the condition pages connected to this study.