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DASH diet put to the test against kidney stones

NCT ID NCT06210009

Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a DASH-style diet (rich in fruits, vegetables, and low-fat dairy) can reduce the risk of kidney stones compared to a typical Western diet. Forty-eight adults with a history of kidney stones will eat specially prepared meals for one week. Researchers will measure urine chemistry to see if the DASH diet lowers stone-forming substances.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
DASH-style diet
What this could lead to
If it works, this could show that a healthy diet lowers the risk of forming kidney stones, providing a simple prevention strategy.
What could go wrong
This is a small, short-term study (48 people, 1 week) that only measures urine markers, not actual stone formation. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Birmingham, AL area participants of the Coronary Artery Risk Development in Young Adults (CARDIA) study OR patients of the University of Alabama at Birmingham/Kirklin Clinic * Self-reported, documented, and/or prior imaging-based diagnosis of kidney stone disease * Age 19-89 * Any sex * Any race * Able to provide informed consent * Willing to perform 24-hour urine collections * Willing to consume meals prepared by Bionutrition Unit * No food allergies/intolerance to any of the foods in the study menus * Willing to stop for 7 days before and during study: Multivitamins and/or Dietary supplements (including calcium and vitamin C) Exclusion Criteria: * Dialysis * Kidney transplant recipient * Estimated glomerular filtration rate (eGFR) \<60 ml/min/1.73m2 based on historical laboratory measurements * Renal tubular acidosis * Current use of acetazolamide, topiramate, or zonisamide * Primary hyperparathyroidism or history of parathyroidectomy * Hyperthyroidism * Sarcoidosis * Primary hyperoxaluria * Cystinuria * Nephrotic syndrome * Malabsorptive conditions including inflammatory bowel disease or history of malabsorptive surgery (e.g., Roux-en-Y gastric bypass, small bowel resection) * Urinary retention requiring catheterization * Urinary diversion * Pregnancy * Breastfeeding * Malignancy treated in the past 12 months other than non-melanoma skin cancer

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney stone

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

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