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Could a diabetes pill boost chemo response in breast cancer? new study investigates.

NCT ID NCT05989347

First seen May 27, 2026 · Last updated Jun 18, 2026 · Updated 5 times

Summary

This early-phase study looks at whether adding dapagliflozin, a diabetes drug, to standard chemotherapy changes insulin-related markers in the blood. It involves 20 women with early-stage HER2-negative breast cancer who also have high insulin levels. The goal is to gather safety data and understand how the drug affects insulin resistance, not to treat the cancer directly.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale Cancer Center Smilow Cancer Hospital

    RECRUITING

    New Haven, Connecticut, 06520, United States

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Her2-receptor negative breast cancer hyperinsulinism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.