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Ancient herbal mix put to the test against high cholesterol

NCT ID NCT06700408

Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether a combination of Chinese herbal granules (Dachaihu Decoction and Erzhiwan) can safely lower LDL cholesterol in people with hypercholesterolemia. Participants receive either the herbal formula or a placebo for 8 weeks, followed by 4 weeks of observation. The main goal is to see how much LDL cholesterol drops after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a combination of Chinese herbal granules (Dachaihu Decoction and Erzhiwan with variation)
What this could lead to
If effective, this herbal formula could offer a new option for managing high cholesterol without standard statin drugs.
What could go wrong
This is a small, early-phase trial with only 70 participants. The herbal mixture may not lower cholesterol significantly, and side effects are not yet well understood.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Apr 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-80 years old, any gender; * LDL-C level of 4.1 mmol/L or above (no statin therapy during the screening period); * Be able to maintain a more consistent lifestyle and eating habits throughout the study; * Have a fixed residence and are not expected to move or travel for 8 weeks; * Voluntarily sign the informed consent form. Exclusion Criteria: * Taking drugs that may affect lipid metabolism (such as steroids, sleeping pills, and psychotropic drugs); * Alcohol or drug abuse within the last 3 months; * Known liver function or renal dysfunction; * History of severe cardiovascular and cerebrovascular diseases; or history of psychiatric illness; * Participate in other interventional clinical trials within 3 months before the study, including drugs, supplements, medical devices, etc.; * Known pregnant or lactating women, allergies or allergies to traditional Chinese medicine; * Patients with known secondary hypercholesterolemia.

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Conditions

The condition(s) this trial relates to.

Hypercholesterolemia hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypercholesterolemia

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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