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New drug DA-3501 takes on tough cancers: early trial begins

NCT ID NCT07481357

First seen Mar 24, 2026 · Last updated Jun 24, 2026 · Updated 13 times

Summary

This early-stage trial tests an experimental drug called DA-3501 in people with advanced stomach, gastro-esophageal junction, or pancreatic cancer that has a specific protein (CLDN18.2). The drug is given intravenously every three weeks. The main goals are to find a safe dose and see if it can shrink tumors. About 51 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHA University Bundang Medical Center

    RECRUITING

    Seongnam, Bundang, 13496, South Korea

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam, Bundang, 13620, South Korea

  • Severance Hospital

    RECRUITING

    Seoul, Seoul, 03722, South Korea

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DA-3501 (an experimental drug given intravenously every three weeks)

What this could lead to

If it works, this could point toward a new treatment option for advanced stomach and pancreatic cancers that have a specific marker (CLDN18.2).

What could go wrong

This is a very early (Phase 1) trial with only 51 participants. The main goal is safety and dosing, not proof of effectiveness. Many early cancer drugs do not succeed in later trials.

Conditions

The condition(s) this trial relates to.

gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.