New drug DA-3501 takes on tough cancers in first human trial

NCT ID NCT07481357

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing an experimental drug called DA-3501 in 51 adults with advanced stomach, gastro-esophageal junction, or pancreatic cancers that have a specific protein (CLDN18.2). Participants receive the drug by IV once every three weeks. The main goals are to find a safe dose and see if the drug can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DA-3501 (an experimental drug given by IV every three weeks)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced stomach or pancreatic cancers that express a specific marker (CLDN18.2).

What could go wrong

This is a very early, first-in-human trial with only 51 participants. The drug may not shrink tumors or could cause serious side effects. Success is far from guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm gastroesophageal cancer gastroesophageal junction adenocarcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHA University Bundang Medical Center

    RECRUITING

    Seongnam, Bundang, 13496, South Korea

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam, Bundang, 13620, South Korea

  • Severance Hospital

    RECRUITING

    Seoul, Seoul, 03722, South Korea