Can a single CT scan replace two tests for bladder cancer?
NCT ID NCT00567684
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two imaging techniques—CT urography (CTU) and intravenous urography (IVU)—in 133 bladder cancer patients to see if CTU alone can effectively monitor the disease. Researchers want to determine if CTU provides clear enough images of the urinary tract to replace the need for both scans. The goal is to simplify future monitoring for patients at risk of urothelial tumors.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could show that CTU scans alone are reliable for monitoring bladder cancer, potentially replacing the need for IVU scans.
- What could go wrong
- This is a small pilot study (133 participants) comparing two imaging methods, not testing a new treatment. Results may not change current practice without larger trials.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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133 people
The number who actually took part.
- Started
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Nov 2007
- Expected to finish
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Nov 2034
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients who will undergo IVU using digital tomosynthesis and staging abdomino-pelvic CT as part of their routine care will be invited to participate in this study. 2. Patients who have been referred for CTU will also be invited to participate in the study. 3. Such patients will typically 1. Have histologically proven TCC, or 2. Have bladder tumors of Stage ≥ T3, or 3. Had cystectomies for bladder cancer, or 4. Upper tract TCC. 4. \>18 years age. 5. Written informed consent will be obtained from patients. Patient exclusion criteria: 1. Elevated serum creatinine of \>2 2. Allergy to intravenous CT contrast media 3. Ureteral stint present or removed within six weeks 4. Women of child bearing potential
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Other studies related to the condition(s) this trial covers.
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