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Hidden in plain sight: old CT scans may predict fractures better than current tests

NCT ID NCT07487688

Knowledge-focused Sponsor: Technical University of Munich Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether using regular CT scans (already done for other reasons) can better predict the risk of spine fractures in people over 50, compared to the standard FRAX risk score. Researchers analyzed CT images from nearly 2,800 adults taken five years apart. The goal was to see if bone density and hidden fractures on CT could identify high-risk individuals more accurately, without extra tests or radiation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2,799 people

The number who actually took part.

Started

Feb 2003

Finished

Oct 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Consecutive patients from the local imaging database that received a CT scan including at least T6 to L4 (=baseline) and a second CT scan after at least 5 years including at least T6 to L4 (=5 years follow-up)

Ages

40 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Baseline CT and 5 years follow-up CT including parts of the lumbar spine Exclusion Criteria: * CT: No sagittal reformations or axial slices ≤3 mm * CT: No inclusion of at least T6 to L4 * No BMI data available

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Conditions

The condition(s) this trial relates to.

osteoporosis spinal fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fracture risk assessment Osteoporosis Osteoporotic fracture of vertebra

Contacts and locations

Locations

  • Klinikum rechts der Isar

    München, 81675, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.