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New CT method may pinpoint stroke blockages faster

NCT ID NCT07347587

Diagnosis Sponsor: Xuanwu Hospital, Beijing Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a special type of CT scan (multimodal CT) can more accurately identify the blocked artery in people with medium vessel occlusion stroke. Researchers will compare this method to standard CT scans in 622 adults who had a stroke within the last 24 hours. The goal is to see if the newer scan helps doctors make faster and more precise diagnoses.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to faster and more accurate diagnosis of medium vessel stroke, helping doctors choose the right treatment sooner.
What could go wrong
This is an observational study, not a treatment trial. It may show that the new CT method is not significantly better than standard scans, and results may not apply to all stroke patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 622 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

According to previous literature reports, the prevalence of MeVO stroke accounts for 18% of ischemic stroke. It is estimated that the sensitivity of NCCT + CTA in diagnosing MeVO is 74%. Based on multimodal CT, the sensitivity for diagnosing moderate vascular occlusive stroke can be increased by 15%, reaching 89%. The test level is bilateral 0.05, and the confidence level 1 - β = 0.8. Then, at least 622 research subjects are required. Among them, the number of patients with MeVO, N1 = 622 \* 0.18 = 112 cases.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with acute ischemic stroke, without restrictions on gender * Age ≥ 18 years old * The time from onset to treatment is within 24 hours (the onset time is defined as the "last-well-time", and the treatment plan is determined according to the patient's wishes and local clinical experience) * Before the treatment, CT, CTA and CTP examinations were conducted, and the relevant clinical data were complete. Exclusion Criteria: * Patients with acute intracranial hemorrhage * Patients whose CTP original images cannot be processed by the CTP post-processing software * Patients for whom the DICOM format image data of CT, CTP original images and MRI images cannot be obtained, or whose image quality is poor due to various reasons

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Xuanwu Hospital Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100053, China

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