Chill out tooth pain: cold therapy after root canal shows promise
NCT ID NCT07138365
First seen Feb 19, 2026 · Last updated Jun 17, 2026 · Updated 18 times
Summary
This study tested two types of cold therapy (cryotherapy) to see if they could reduce pain and inflammation after root canal treatment for infected lower premolars. Thirty adults with painful tooth infections were randomly assigned to receive either an ice pack on the cheek, a cold saline rinse inside the tooth, or standard care. The researchers measured pain levels and a chemical linked to inflammation (substance P) to compare the approaches.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Ain Shams University
Cairo, Egypt
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