Cold therapy could take the ouch out of blood tests
NCT ID NCT07408011
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if applying cold (cryotherapy) to the wrist before a blood draw from the artery can reduce pain. It involves 258 adults with chronic respiratory diseases who need this test. The goal is to find a simple, drug-free way to make the procedure less painful.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 258 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient with a respiratory condition requiring arterial blood gas sampling via radial puncture * Patients able to assess their pain using a numerical rating scale * Patients reporting a pain score of 0 on the numerical scale at the wrist prior to sampling * Patients with no contraindications or allergies to local anesthetics such as lidocaine/prilocaine * Patients aged 18 years or older * Patients affiliated with or benefiting from a social security scheme * Patients able to give consent and who have signed an informed consent form Exclusion Criteria: * Patients reporting a pain score \>0 on the numerical rating scale before sampling * Emergency context requiring immediate arterial blood gas results * Patients for whom radial arterial puncture is not feasible * Known hypersensitivity to local amide-type anesthetics or any component of the lidocaine/prilocaine cream * Pregnant or breastfeeding women * Refusal to participate * Patients under legal guardianship or conservatorship
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CH Morlaix
Morlaix, Finistere, 29672, France
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CHU Brest
Brest, Finistere, 29200, France
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