Freezing nerves during lung transplant could cut opioid use
NCT ID NCT07281118
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new way to manage pain after a double lung transplant. Instead of relying only on strong pain medicines, doctors will use a cold-therapy probe during surgery to numb the nerves near the incision. The goal is to see if this method reduces the need for opioids and helps patients recover more comfortably. About 148 adults receiving a double lung transplant will take part.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 148 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults ≥18 years of age * Undergoing double lung transplantation via bilateral thoracotomies or clamshell incision Exclusion Criteria: * Multi-organ transplant recipients * Redo lung transplant recipients
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Baylor University
NOT_YET_RECRUITINGWaco, Texas, 76706, United States
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University of California Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
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University of California San Francisco
NOT_YET_RECRUITINGSan Francisco, California, 94143, United States
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