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Freezing out tumors: new hope for rare desmoid disease

NCT ID NCT02476305

First seen Jan 30, 2026 · Last updated Jun 22, 2026 · Updated 20 times

Summary

This study tested a freezing technique called cryoablation on 50 adults with desmoid tumors that had grown despite medical treatment. The goal was to stop tumor growth and ease symptoms without surgery. Researchers used MRI to guide the freezing and check results one year later.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Service d'Imagerie Interventionnelle

    Strasbourg, Alsace, 67091, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cryoablation (freezing therapy using cryoprobes)

What this could lead to

If successful, cryoablation could provide a non-surgical way to control desmoid tumors, reduce pain, and improve quality of life for patients who have not responded to other treatments.

What could go wrong

This is a small, early-phase study (50 participants) with no control group. The procedure may not work for all tumor locations, and there is a risk of incomplete destruction or recurrence.

Conditions

The condition(s) this trial relates to.

desmoid tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.