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Targeted drug crizotinib tested against hard-to-treat MET-amplified cancers

NCT ID NCT06357975

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 28 times

Summary

This study tests the drug crizotinib in people whose advanced or treatment-resistant solid tumors, lymphoma, or multiple myeloma have a specific genetic change called MET amplification. Crizotinib works by blocking signals that help cancer cells grow and spread. The main goal is to see how many patients' tumors shrink or disappear, and researchers also track how long the cancer stays under control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.