Targeted drug crizotinib tested against hard-to-treat cancers with MET gene flaw

NCT ID NCT06357975

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 27 times

Summary

This study tests the drug crizotinib in people with advanced or treatment-resistant solid tumors, lymphoma, or multiple myeloma that have a specific genetic change called MET amplification. Crizotinib works by blocking signals that help cancer cells grow and spread. The main goal is to see how many patients' tumors shrink or disappear, and researchers also track how long patients live without their cancer getting worse.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.