Cranberry juice may boost brainpower and stress resilience
NCT ID NCT07453537
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study looks at whether drinking cranberry juice every day for 70 days can improve how well healthy adults aged 30 to 55 handle stress and multitask. Participants will do mental and physical tasks while researchers measure their thinking, mood, and stress levels. The study also checks if changes in gut bacteria play a role.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 84 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At least 110 pounds * Between 30 and 55 years * BMI between 18.9 and 29.9 kg/m² * A minimum education level of high school or above Exclusion Criteria: * Heavy caffeine users (consuming more than 300 mg/day or more than two cups of coffee per day) * Alcohol consumption exceeding three drinks per week * A smoking history of 10 years or more, or current use of cannabis products * Uncontrolled hypertension * Clinically diagnosed illnesses such as diabetes, cardiovascular disease, neurological disorders, or mental health conditions * Participants currently taking prescribed anti-inflammatory medications, antibiotics, or antidepressants that may affect study outcomes, particularly those related to blood and fecal sample analysis * Individuals who regularly take vitamin or mineral supplements and are unwilling to discontinue them for the duration of the study will not qualify. * Participants must be willing to maintain their current daily routine and lifestyle, undergo body weight and height measurements, and notify study coordinators of any illnesses or significant adverse life events during the study period * Those with specific dietary restrictions that prevent them from consuming the standardized breakfast sandwich required in the study protocol * Participants must successfully complete the on-site multitasking task as a screening measure prior to signing consent. * Beck's Depression Inventory score of 21 or higher * Beck's Anxiety Inventory score of 21 or higher * A history of severe suicidal tendencies, or seasonal depression * Pregnancy and breastfeeding (Female participants must complete four pregnancy tests throughout the study and track their menstrual cycle. Those unwilling to comply with these requirements will not be eligible.) * Potential participants must not have taken any anti-inflammatory medications, antibiotics, or antidepressants within the past three months prior to the start of the study * Individuals who were previously enrolled in IRB#202300950 will be excluded due to the learning effect of cognitive tests, ensuring accurate data collection for this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Florida
RECRUITINGGainesville, Florida, 32608, United States
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