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Sleep apnea study tests pill to boost CPAP use and brain power

NCT ID NCT07332442

First seen Jan 12, 2026 · Last updated Jun 23, 2026 · Updated 29 times

Summary

This study tests whether a sleep medication called eszopiclone can help people with obstructive sleep apnea use their CPAP machine more consistently and improve their thinking skills. About 250 adults with a new sleep apnea diagnosis will receive either eszopiclone or a placebo for three months while using CPAP. Researchers will track how often participants use CPAP and measure changes in attention and daytime sleepiness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Yale Centers for Sleep Medicine

    RECRUITING

    North Haven, Connecticut, 06347, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Eszopiclone (a sleep medication)

What this could lead to

If it works, this could point toward a way to help people with sleep apnea stick with CPAP therapy and possibly improve their thinking and daytime alertness.

What could go wrong

This is a Phase 3 trial, but it's still testing a hypothesis. The sleep aid may not improve CPAP use or thinking, and could cause side effects like drowsiness or dizziness.

Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.