Healthy Workers' COVID antibodies tracked for a year
NCT ID NCT04369066
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study followed nearly 2,000 healthy employees from Institut Curie and Institut Pasteur to see how their immune systems responded to the SARS-CoV-2 virus over time. Participants gave blood samples at four points over a year to test for antibodies. The goal was to learn how long antibodies last and how common past infection was in this group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help us understand how long COVID-19 antibodies last in healthy people and improve future testing strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It only measures antibodies and cannot determine protection from infection or severe disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
1,971 people
The number who actually took part.
- Started
-
Apr 2020
- Finished
-
May 2022
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Person, adult volunteer outside of any acute infectious episode with SARS-CoV-2\* (see paragraph indication), working at the Institute Curie and able to exercise their professional activity on one of the 3 sites of the Institute Curie: Paris, Orsay or Saint Cloud, or on the Campus of the Institute Pasteur. 2. Person aged 18 or over. 3. Information and consent of the person to the procedures related to the study (cf. information note / consent). From November 2020, person having presented at least one of the following criteria since January 2020: * A positive diagnostic test for SARS-COV-2 by PCR on a nasopharyngeal sample or antigenic test, * A positive SARS-CoV-2 serology, * An anosmia or / and an ageusia, * A respiratory infection \*\* associated with digestive signs \*\* whatever the working methods during confinement \* Subjects who are not showing active SARS-CoV-2 infection are considered volunteers at the time of inclusion: people with no clinical signs \*\* suggestive of SARS-CoV-2 infection at the time of collection or having had an end of symptoms for more than 7 days \[1\]. \*\* fever, fatigue, cough, shortness of breath, difficulty to breath, loss of taste or smell, headache, body aches, conjunctivitis or cold, digestive problems (vomiting, diarrhea), whether or not the signs led to sick leave, treatment and / or hospitalization \[2\]. Exclusion Criteria: * Declaration by the subject of signs suggestive of Coronavirus Infectious Disease 2019 (COVID-19) infection with SARS-CoV-2 in progress or for which the end of symptoms dates from less than 7 days * Inability to submit to study monitoring for geographic, social or psychological reasons
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Volunteers from the institute curie and institute pasteur staff who are not showing active SARS-CoV-2 infection are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institut Curie
Paris, 75005, France
-
Institut Pasteur
Paris, 75015, France