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A simple cough measurement may help doctors decide when to safely remove a breathing tube

NCT ID NCT07737483

Diagnosis Sponsor: Hospital H+ Queretaro Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether measuring a patient's cough strength before removing a breathing tube can predict who will need the tube put back in. Researchers will use a special algorithm that accounts for whether the patient can cough on command or only reflexively. The goal is to give ICU doctors a better tool to avoid failed extubation, which can lead to serious complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If accurate, this cough-based algorithm could give ICU doctors a reliable, bedside tool to predict which patients are ready to breathe on their own, potentially reducing failed extubations and complications.
What could go wrong
This is an observational diagnostic study, not a treatment trial. The algorithm may not prove accurate enough to change clinical practice, and results may not apply to all ICU populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult ICU patients receiving invasive mechanical ventilation who successfully complete a spontaneous breathing trial and are considered clinically ready for planned extubation. Participants are recruited consecutively from participating tertiary-care intensive care units.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (≥18 years) admitted to the ICU who received invasive mechanical ventilation for \>24 hours and successfully completed a Spontaneous Breathing Trial (SBT). Exclusion Criteria: * Prior indication for tracheostomy (e.g., severe maxillofacial trauma, upper airway obstruction). * Self-extubation or accidental extubation. * Decision to withhold or withdraw life-sustaining treatments. * Severe primary neuromuscular diseases.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Extubation failure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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