New contact lens trial offers hope for astigmatism sufferers
NCT ID NCT06751225
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested how well people with astigmatism who had never worn contact lenses liked a new type of soft lens that is replaced every week. Forty adults wore the lenses for about three weeks and reported on their vision and comfort. The goal was to see if these lenses could be a good option for beginners.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- weekly replacement soft contact lenses
- What this could lead to
- If successful, this could show that weekly replacement soft contact lenses are a comfortable and effective option for people with astigmatism who have never worn contacts before.
- What could go wrong
- This is a small, completed study with only 40 participants. Results may not apply to everyone, and the lenses might not work well for all types of astigmatism.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Subjects must be new to contact lenses and have astigmatism of -0.75 or greater (within the parameters available for the P7fA lenses) 2. Subjects must have 20/20 or better best corrected visual acuity. 3. Good general health (defined by medication use that has not changed within the last month and the absence of medical conditions or treatments that are deemed confounding to the data as determined by the PI) 4. Ability to give informed consent 5. Willing to spend time for the study. Subjects will be required to attend three study visits and wear contact lenses on days between study visits. 6. Willing and able to wear contact lenses for at least 8 hours per day for 5 days per week during the study as daily wear. 7. Currently not using eye lubricating drops and willing to not use during study. 8. Either gender and 18-40 years of age. 9. Any racial or ethnic origin Exclusion Criteria: 1. Any active ocular inflammation or infection. 2. Has a systemic condition that in the opinion of the investigator may affect a study outcome variable. 3. Are presbyopic and require or habitually uses reading glasses for near work 4. Is using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable 5. History of refractive surgery 6. Meets the diagnosis of dry eye disease with OSDI screening score ≥13. 7. Known history of allergy or sensitivity to contact lens solutions and/or sodium fluorescein 8. Is pregnant or lactating or planning a pregnancy during enrollment in the study 9. Is participating in another clinical research study that includes invasive ocular tests 10. An inability to perform contact lens application and removal after instruction.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Ohio State University College of Optometry
Columbus, Ohio, 43210, United States