Stroke survivors may regain arm function with intensive therapy
NCT ID NCT05492513
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a therapy called Constraint-Induced Movement (CI) Therapy for adults who had a stroke at least 6 months ago and have mild weakness in one arm. The therapy involves daily training to improve arm and hand use, along with strategies to encourage using the weaker arm in daily life. The goal is to see if this approach helps people use their affected arm more and better. The study is small, with 12 participants, and is currently recruiting.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 12 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2022
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At least 6 months post stroke * The ability to demonstrate the minimum UE active movement criteria of 20 degrees of wrist extension from a fully flexed position, 10 degrees of thumb extension or abduction, and 10 degrees of extension of all finger joints. * Mean score of \>2.5 on the Motor Activity Log indicating the participant's use of the more-affected UE. Exclusion Criteria: * Score\< 24 on the Mini Mental State Exam * Inability to answer the MAL questions and/or provide informed consent * The inability to come in to the laboratory setting for treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
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