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Brain-Directed chemo combo shows promise for tough breast cancer spread

NCT ID NCT06230055

First seen Jan 08, 2026 · Last updated May 24, 2026 · Updated 20 times

Summary

This study looks at whether giving chemotherapy directly into the fluid around the brain (via a small device called an Ommaya reservoir) along with standard body-wide chemo works better than standard chemo alone for people with HER2-negative breast cancer that has spread to the brain lining. About 37 adults with this condition will be randomly assigned to one of the two treatments. The main goal is to see if the combination helps delay worsening of the brain disease or death.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.