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Can brain training help TBI patients remember to remember?

NCT ID NCT04065477

Symptom relief Sponsor: Kessler Foundation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study tests a computer-based cognitive rehabilitation program designed to improve thinking skills, particularly time-based prospective memory—remembering to do things at a specific time—in people who have had a moderate-to-severe traumatic brain injury (TBI) at least a year ago. Participants will complete up to 32 sessions over 16 weeks, and researchers will measure how well they tolerate the program, how many sessions they attend, and any changes in memory and strategic thinking. The goal is to see if this approach is feasible and worth studying further.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
computer-based cognitive rehabilitation (CBCR)
What this could lead to
If this approach works, it could offer a structured, at-home method to help people with traumatic brain injury improve memory and thinking skills.
What could go wrong
This is a small feasibility study, so results may not apply broadly. The intervention may be difficult to tolerate or may not produce meaningful cognitive gains.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

9 people

The number who actually took part.

Started

Oct 2019

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 59 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Sustained a moderate-to-severe TBI at least one year prior to assessment * Fluent in English * Demonstrate impairment in strategic cognitive abilities Exclusion Criteria: * Significant neurological history other than TBI * Significant psychiatric history (e.g., bipolar disorder, schizophrenia) * Significant substance abuse history * Steroid and/or benzodiazepine use

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic brain injury traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Traumatic brain injury

Contacts and locations

Locations

  • Kessler Foundation

    East Hanover, New Jersey, 07936, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.