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New study tests outreach calls and texts to boost smoking cessation

NCT ID NCT05382221

Disease control Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a program called Comprehensive Chronic Care (CCC) that uses regular phone calls, texts, and mailings to encourage smokers to quit. Nearly 1,000 adult smokers from primary care clinics were randomly assigned to receive either CCC or standard care (one annual offer of help). The main goal was to see if more people in the CCC group had stopped smoking after 18 months, confirmed by a breath test. The study also looked at cost-effectiveness and how many people engaged with the program.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Comprehensive Chronic Care (CCC) - a program of outreach calls, texts, and mailings to offer smoking cessation treatment
What this could lead to
If successful, this approach could provide a more effective way to help smokers quit, reducing smoking-related diseases.
What could go wrong
This is a completed study, so results are available but may not apply to all populations. The intervention is behavioral, so success depends on individual motivation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

979 people

The number who actually took part.

Started

Aug 2022

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * On smoking registry at a participating clinic OR report current smoking at a clinic visit * Smoked cigarettes every day in the past 30 days (with or without other forms of tobacco or nicotine) * Able to participate in informed consent activities (e.g., reports understanding the nature of the study and consent) * Able to speak and read English. Exclusion Criteria: * Activated healthcare power of attorney or cognitive impairment that would preclude informed consent.

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Conditions

The condition(s) this trial relates to.

Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Smoking abstinence Smoking cessation

Contacts and locations

Locations

  • Advocate Aurora

    Milwaukee, Wisconsin, 53204, United States

  • UW Health

    Madison, Wisconsin, 53792, United States

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