Heart valve showdown: which replacement lasts longer in seniors?
NCT ID NCT07210541
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at two surgical options for replacing a worn-out aortic heart valve in people aged 60-74. Researchers compared a standard stented biological valve with a donated human valve (allograft) to see which led to better survival and fewer complications. The goal was to find the safest, most effective choice for these patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
93 people
The number who actually took part.
- Started
-
Jan 2017
- Finished
-
Sep 2025
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with degenerative aortic valve disease, age 60-74 years
- Ages
-
60 to 74 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with degenerative aortic valve disease not emendable for aortic valve repair * Elective surgery Exclusion Criteria: * Left ventricle ejection fraction less than 40% * Redo surgery * Indication for concomitant mitral valve replacement * Aortic valve/root endocarditis * Severe COPD * Dialysis patients
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Allograft are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Why do stem cell transplant patients skip meds? new study investigates
- Custom 3D-printed bone blocks may improve dental implant success
- Blood test may spot hidden heart valve infections
- Dental bone graft showdown: which material keeps your jaw stronger?
- New bone graft aims to ease pain from spine fractures
- Less invasive heart valve replacement may be better for seniors with small valves