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Could a simpler surgery be just as effective for aggressive uterine cancer?

NCT ID NCT06900582

First seen Feb 20, 2026 · Last updated Apr 30, 2026 · Updated 10 times

Summary

This study compares two surgical approaches for people with early-stage, high-risk endometrial cancer that has a p53 gene mutation. Half of the 374 participants will receive the standard extensive lymph node removal, while the other half will get a less invasive sentinel node biopsy. The goal is to see if the simpler procedure can control the cancer just as well, with fewer side effects and better quality of life.

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