Failed your colonoscopy prep? scientists test three rescue options to find the best clean.
NCT ID NCT07557173
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial compares three different bowel-cleansing regimens for adults who need a repeat colonoscopy because their first prep didn't work well enough. Participants are randomly assigned to take one of three laxative combinations before their second colonoscopy. The study measures how clean the bowel gets and how satisfied patients are with the process.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- polyethylene glycol (PEG) with or without bisacodyl or ascorbic acid
- What this could lead to
- If successful, this study could identify the most effective rescue bowel preparation, making repeat colonoscopies easier and more reliable for patients who had a failed prep.
- What could go wrong
- This is a small, single-center trial (220 participants) comparing existing drugs, not a new breakthrough. Results may not apply to all patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 220 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older * Prior inadequate bowel preparation (adequately performed) requiring repeat colonoscopy * Scheduled to undergo repeat outpatient colonoscopy * Ability to provide informed consent Exclusion Criteria: * Age younger than 18 years * Inability to provide informed consent * Contraindication to any study bowel preparation regimen or colonoscopy * Known or suspected bowel obstruction or severe gastrointestinal motility disorder * Pregnancy or breastfeeding * Participation considered inappropriate by the investigators for clinical or safety reasons
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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San Pio Hospital
RECRUITINGBenevento, Italy
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